STUDY

Root coverage using coronally advanced flap with porcine-derived acellular dermal matrix or subepithelial connective tissue graft: a randomized controlled clinical trial.

https://pubmed.ncbi.nlm.nih.gov/32382931/

Tanaka Suzuki K, de Jesus Hernandez Martinez C, Irie Suemi M, Bazan Palito D, Reis Messora M, Scombatti de Souza SL, Belem Novaes Jr A, Chaves Furlaneto F A, Taba Jr M.

Aim:
Investigation of a porcine-derived acellular dermal matrix (MD – mucoderm®) in root coverage procedures combined with extended coronally positioned flap (eCAF), in comparison to the subepithelial connective tissue graft (SCTG) associated with the eCAF in a split-mouth, double-masked, randomized controlled clinical trial.

Materials and methods:
Eighteen adult patients presenting bilateral type 1 gingival recession were randomly assigned to SCTG or MD groups. Clinical and patient-based outcomes (probing depth (PD), clinical attachment level (CAL), gingival recession height (RH), gingival recession width (GRW), keratinized tissue height (KTH), keratinized tissue thickness (KTT)) were recorded at 3 and 6 months after the surgical procedure.

Results/Conclusion:
A significant reduction in the mean recession height of 3.33 ± 0.89 mm to 1.24 ± 1.10 mm (mucoderm®) and 3.21 ± 0.8 mm to 0.83 ± 0.86 mm (SCTG) was found in both groups. Six patients in the mucoderm® group and eight in the control group obtained complete root coverage. The keratinized tissue height and thickness (KTT) showed a significant increase after 3 and 6 months in both groups. The average KTT gains were 0.39 ± 0.4 mm (mucoderm®) and 0.51 ± 0.5 mm (SCTG) (p < 0.05). Performing multivariate analysis suggests that mucoderm® addition to coronally advanced flaps may be similar to SCTG.
mucoderm® achieved similar results in comparison to SCTG. Regarding reduction of patient morbidity, mucoderm® can be used as an alternative grafting material for the treatment of gingival recessions.

Dr. Mario Taba

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