maxresorb®

INNOVATIVE BIPHASIC CALCIUM PHOSPHATE

maxresorb® is a safe, reliable and 100% synthetic bone graft substitute with controlled resorption properties and excellent handling characteristics. The fully synthetic nature of maxresorb® ensures its safety and eliminates any risk of infection.

Biphasic activity
maxresorb® shows an ideal homogenous, biphasic, composition of 60% hydroxyapatite (HA) and 40% beta-tricalcium phosphate (β-TCP) [1,2]. This composition is reflected into the controlled resorption behavior of maxresorb®  [3,4], which results in an initial integration of the particles followed by a complete resorption. While the fast resorption of β -TCP continuously increases the porosity of the material promoting tissue integration by allowing ingrowth of cells and blood vessels, the HA component provides volume stability for an extended time period.

 

SPECIFICATIONS & FACTS

IDEAL OSTEOCONDUCTIVITY

The osteoconductivity of maxresorb® is achieved by a matrix of interconnected pores and a very high porosity of approx. 80%, with pore sizes ranging from 200-800 μm. The high macroporosity of maxresorb® ensures an efficient osteogenic cell growth and promotes the regeneration of vital bone. In turn, the microporosity and surface roughness of maxresorb® facilitate diffusion of biological fluids and cell attachment.

maxresorb® is thus an ideal scaffold for the migration of bone forming cells and binding of signaling molecules, which can accelerate tissue integration and regeneration [5].
maxresorb_bone

 

CLINICAL APPLICATION

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PROPERTIES

– 100% synthetic and safe
– Biphasic homogenous composition
– Controlled full resorption/remodeling
– Rough and hydrophilic surface
– High porosity/interconnected pores

INDICATIONS

maxresorb® is a very versatile bone substitute that can be used in virtually all indications. It is therefore an ideal alternative to bovine bone especially in sites with a high regenerative potential such as the post-extraction socket and sinus.

IMPLANTOLOGY, PERIODONTOLOGY AND ORAL AND CMF SURGERY

– Sinus lift
– Ridge augmentation
– Intraosseous defects
– Osseous defects
– Furcation defects
– Socket preservation

PRODUCT INFORMATION

RELATED PRODUCTS

LITERATURE

[1]  Gauthier et al. (1999). Elaboration conditions influence physicochemical properties and in vivo bioactivity of macroporous biphasic calcium phosphate ceramics. Journal of materials science. Materials in medicine 10:199–204.
[2]  Schwartz et al. (1999). Biphasic synthetic bone substitute use in orthopaedic and trauma surgery: clinical, radiological and histological results. Journal of materials science. Materials in medicine 10:821–825
[3]  Daculsi (1998). Biphasic calcium phosphate concept applied to artificial bone, implant coating and injectable bone substitute. Biomaterials 19:1473–1478.
[4]  Ducheyne et al. (1993). The effect of calcium phosphate ceramic composition and structure on in vitro behavior. I. Dissolution. Journal of biomedical materials research 27:25–34
[5] Eriberto Bressan et al. Donor Age-Related Biological Properties of Human Dental Pulp Stem Cells Change in Nanostructured Scaffolds. PLOS One, Nov 2012, VOl 7, Issue 11; e49146.