collafleece®

RESORBABLE COLLAGEN FOR WOUND MANAGEMENT

collafleece® is a wet-stable, porcine collagen sponge with highly efficient hemostatic properties. Its natural porous collagen structure supports the hemostasis and controls the natural healing of the wound. Owing to its spongy collagen structure, the collafleece® resorbs within ~2-4 weeks.

SPECIFICATIONS & FACTS

FAST HEMOSTASIS AND STABILIZATION OF THE BLOOD CLOT

The efficacy of collafleece®e is based on the well-known characteristics of collagen. The process of blood clotting comprises a complex series of reactions induced by the adhesion of platelets to the collagen fibers, which results in the formation of a thrombus by platelet aggregation. The secretion of coagulation factors is thereby triggered, which initiate further reactions as the formation of a fibrin clot [1,2,3]. The fast clotting reaction through collafleece® is particularly helpful when treating hemostatic compromised patients [4].

PROPERTIES

Highly efficient hemostatic collagen
Fast resorption by enzymatic degradation (2-4 weeks)
Easy application
Maintains integrity in presence of blood and during application
Wound protection/wound healing

INDICATIONS

collafleece® is a hemostatic collagen sponge indicated to support wound healing and control bleedings.

IMPLANTOLOGY, PERIODONTOLOGY AND ORAL AND CMF SURGERY

– Protection and hemostatic treatment of minor oral wounds
– Portection of the Schneiderian membrane
– Covering of biopsy or transplant harvesting sites
– Protection and hemostatic treatment after tooth extraction

POSTER/ARTICLE:

  • Ozcelik O, Seydaoglu G, Haytac CM. Diode laser for harvesting de-epithelialized palatal graft in the treatment of gingival recession defects: a randomized clinical trial. J Clin Periodontol. 2016; 43(1):63-71. LINK
  • Zirk M, Fienitz T, Edel R, Kreppel M, Dreiseidler T, Rothamel D. Prevention of post-operative bleeding in hemostatic compromised patients using native porcine collagen fleeces-retrospective study of a consecutive case series. Oral Maxillofac Surg. 2016. [Epub ahead of print]. LINK

RELATED PRODUCTS

LITERATURE

[1] Nieswandt B and Watson SP. Platelet-collagen interaction: is GPVI the central receptor? Blood. 2003; 15;102(2):449-61. http://www.ncbi.nlm.nih.gov/pubmed/12649139
[2] Nuyttens BP, Thijs T, Deckmyn H, Broos K. Platelet adhesion to collagen. Thromb Res. 2011; 127 Suppl 2:S26-9. http://www.ncbi.nlm.nih.gov/pubmed/21193111
[3] Versteeg H.H, Heemskerk J.W.M, Levi M, Reitsma P.H. New fundamentals in hemostasis. Physiological Reviews 2013; 93(1): 327-358.
[4] Zirk et al. Prevention of post-operative bleeding in hemostatic compromised patients using native porcine collagen fleeces-retrospective study of a consecutive case series. Oral Maxillofac Surg. 2016. [Epub ahead of print] http://www.ncbi.nlm.nih.gov/pubmed/27139018[5] Morimotot et al. 2008. Hemostatic management of tooth extractions in patients on oral antithrombotic therpy. J Maxillofacial Surg 66:51.